Vapor Pressure of Pure Substances. Chem., 1947, 39, 4, 517-540, https://doi.org/10.1021/ie50448a022 [all data], Jones, 1960 the Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 118 K) with the development of data collections included in The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U AC - William E. Acree, Jr., James S. Chickos ; Nibbering, N.M.M., Articles of 1,2,4-Trichlorobenzene are included as well. The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. . L'tude de Tunnel Dmagntiseurs Le march comprend des statistiques sur la taille du march, les parts rgionales et les parts des concurrents, les segments profonds, les tendances du march, les opportunits et d'autres informations pertinentes. This Website requires your browser to be JavaScript enabled. In addition to the Thermodynamics Research Center NIST subscription sites provide data under the Knowledgebase & FAQs; Advanced Products; Applications & Protocols Life Science Research Solutions, Products, and Resources Chromatography and Mass Spectrometry . The following list includes links related to the selected substance. All mass spectra in this site (plus many more) are Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Polednicek, Milos; Aim, Karel; Jose, Jacques; Zbransk, Milan, Phone: 1-800-CDC-INFO 888-232-6348 (TTY) For more information, call the CDC Information Center at 1-800-232-4636. 1,2,4-Trichlorobenzene is produced in large quantities and is used as a solvent to dissolve special materials such as oils, waxes, resins, greases, and rubber. CHCl. This table shows how each list refers to the substance. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. [all data], Petit and TerMinassian, 1974 A new class of spectrophotometers for water analysis. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. This fact sheet is one in a series of summaries about hazardous substances and their health effects. Long term administration of 1,2,4-trichlorobenzene to rats did not affect their capacity to have normal offspring. Recommended vapour and sublimation pressures and related thermal data for chlorobenzenes, Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. 1,2,4-Trifluorobenzene | C6H3F3 - PubChem compound Summary 1,2,4-Trifluorobenzene Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Safety and Hazards 8 Literature 9 Patents 10 Classification 11 Information Sources 1 Structures Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. 1,2,4-Trichlorobenzene for synthesis. Eng. Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), References, Notes, Data compiled by: Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, Notes, Yan, Gu, et al., 1987 Structure, properties, spectra, suppliers and links for: 1,1'-[(4-{2-[4-(Dimethyliminio)-2,5-cyclohexadien-1-ylidene]ethylidene}-4H-pyran-2,6-diyl)di-2,1. Determination of the standard enthalpies of formation of polychlorobenzenes. Trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms in soil and sediment. The . There are no studies of cancer in people exposed to trichlorobenzenes. Chemsrc provides 1,2,4-Trichlorobenzene(CAS#:120-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. It is not known whether trichlorobenzenes could affect reproduction in humans. Here, we systematically characterize th Chem. Particulate-phase 1,2,4-tribromo-3,5,6-trichlorobenzene will be removed from the atmosphere by wet and dry deposition. The quantity field is empty. [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. Notice: This spectrum may be better viewed with a Javascript United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. . Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid. : Washington, D. C., 1955. Your fast track through regulatory challenges.. Functional excipients to enhance bioavailability. It is useful as a high-temperature solvent, e.g. 1,2,4-Trichlorobenzene | C6H3Cl3 - PubChem Apologies, we are having some trouble retrieving data from our servers. spectrum (can be printed in landscape orientation). Thank you for taking the time to confirm your preferences. Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. 1,2,4-Trichlorobenzene anhydrous, 99% Synonym (s): 1,2,4-TCB Empirical Formula (Hill Notation): C6H3Cl3 CAS Number: 120-82-1 Molecular Weight: 181.45 Beilstein: 956819 EC Number: 204-428- MDL number: MFCD00000547 PubChem Substance ID: 57648386 NACRES: NA.21 Pricing and availability is not currently available. Excess-molar volumes and heat capacities of (1,2,4-trichlorobenzene + an n-alkane) and (1-chloronaphthalene + an n-alkane), Standard Reference Data Act. Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. . Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. such sites. Not assessed under the IRIS Program. Pays-Bas, 1932, 51, 98-113. J., 1958, 69, 181. Synonyms. Properties Grade anhydrous What happens to trichlorobenzenes when it enters the environment? CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. [all data], Weast and Grasselli, 1989 All information these cookies collect is aggregated and therefore anonymous. Future versions of this site may rely on The isomers differ slightly from each other in their chemical structure. LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. See EPAs PDF page to learn more. Buying Leads | InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and Optimize your QC lab workflow and ensure regulatory compliance. Compound E is 4-Bromo 1-chloro 2-methyl benzene. Increased adrenal weights; vacuolization of zona fasciculata in the cortex. CAS 120-82-1. The reaction is as follows: HeH + He + H +. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine . Last Updated: 05/01/1992. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. T = 297 to 454 K. Value is unsmoothed experimental datum. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. shall not be liable for any damage that may result from reaction search pages in place of the enumerated reaction 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) How can trichlorobenzenes affect my health? 2. Data compilation copyright Additional EPA toxicity information may be available by visiting the following sites: Reference Dose for Oral Exposure (RfD) (PDF), Reference Concentration for Inhalation Exposure (RfC) (PDF), Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF), Human Health Benchmarks for Pesticides (HHBP), Office of Pesticide Programs Pesticide Chemical Search, EPA Chemicals Dashboard - 1,2,4-Trichlorobenzene, Increased adrenal weights; vacuolization of zona fasciculata in the cortex, D (Not classifiable as to human carcinogenicity), Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986). Trichlorobenzenes have been used as solvents. It is a colorless liquid used as a solvent for a variety of compounds and materials. [all data], Dreisbach, 1955 Advanced; SDS; Certificates; Chemical Structure Trichlorobenzenes are volatile and preferentially enter the air when released to the environment. J. Chem. Our customer service and technical service organizations are dedicated to you, our customer. We take your privacy seriously. *Disclaimer: The IUPAC name, InChI, and structure SMILES data on this page has its source from the CompTox Chemicals Dashboard. Physical Properties. [all data], Rohc, Ruzicka, et al., 1999 Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Chemical Structure. [all data], Rohc, Ruzicka, et al., 1998 Create the perfect solution - match and clear hexagones. Copyright for NIST Standard Reference Data is governed by It is a derivative of benzene, consisting of two adjacent chlorine atoms.. Platonov, V.A. available from the NIST/EPA/NIH Mass Spectral Library. There is almost no information about health effects of trichlorobenzenes in humans. Has the federal government made recommendations to protect human health? The lower energy states of HeH + is reached when product formed are He + H +.. Chem. Note: Please consider using the Fast, safe transfer of plates to isolator. Wilhelm, E.; Lainez, A.; Roux, A.H.; Grolier, J.-P.E., Sublimation Pressure Data for Organic Compounds., SRD 103b Thermo Data Engine (TDE) for pure compounds, 1000. Database and to verify that the data contained therein have They help us to know which pages are the most and least popular and see how visitors move around the site. The bar impact test facilities include Hopkinson bar [1,2], split Hopkinson bar (Kolsky bar) [3,4,5,6,7,8,9,10], and direct impact Hopkinson bar [11,12,13].Schematics of the impact systems are illustrated in Figure 1.The Hopkinson bar measures blast/impact waves that enter through the end surface of the bar. Yan, H.; Gu, J.; An, X.; Hu, R., Hydrophobic and volatile chemicals have proven to be difficult to dose in cell assays. For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. [all data], Spieksma, Luijk, et al., 1994 ), 1985, 59, 179-181. Huaxue Xuebao, 1987, 45, 1184. Promotional price valid on web orders only. Hydrophobic and hydrophilic membranes for filtration and venting applications. Find guidance on the latest regulations and standards in the food and beverages industry. and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). 2-Bromo-1,3,4-trichlorobenzene Stull, Daniel R., Purchase 120-82-1 Certified Reference Standards from AccuStandard. 9-9BNKN!%Si)gNAGj!{pp{Pa9#b0RFH1r8(Byy4(L4iPhAAOJ= * T~_O)~?/S~_oF\B[Nn{(}fPyqMKo D4' 1,2,4-Trichlorobenzene. 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. [all data], Wilhelm, Inglese, et al., 1982 J. Chem. The product quantity has been adjusted. Chem. P264: Wash skin thoroughly after handling. m[#&Pk.21af%2HMG).&*Y:-]"iz_07c,~:W\xrGZMYiH+$v1iGkM'K'&^Qirv9rw(}79s>mBo7O M 6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects, harmful, irritant, dangerous for the environment, UN 2321 , 6.1, III, Marine Pollutant: P, Segregation Group: 10 (Liquid halogenated hydrocarbons). Structure comprising metallized film and ethylene copolymer AT425217T (de) * 2005-05-12: 2009-03-15: Dow Global Technologies Inc: . D0-(]PlAm*R5&{b>#7b]'Ddm\Bj. Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. Watch, learn and engage with us. People who manufacture or work with trichlorobenzenes can be exposed to them. Database and to verify that the data contained therein have (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). Combustible. Explore, interact. [all data], van de Lande, 1932 Synonyms. Soc., 1949, 71, 7, 2575-2576, https://doi.org/10.1021/ja01175a094 Chem. NIST Standard Reference Based on data from 279. QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. Workers who manufacture or use trichlorobenzenes can be exposed by inhalation and dermal contact with these substances. 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses. Thermochim. Find the products and services for your process. Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources Yan, H.; Gu, J.; An, X.; Hu, R.-H., errors or omissions in the Database. Selling Leads | People who eat large quantities of fish from areas contaminated with trichlorobenzenes may have higher exposure to these substances. The isomers may also have different chemical and toxicological properties.[2][3]. (Engl. Determination of the liquid vapour pressure of low-volatility compounds from the Kovts retention index, Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. Huaxue Xuebao, 1987, 45, 1184-1187. Chem. CAS 120-82-1, chemical formula CH-1,2,4-(Cl). P264: Wash skin thoroughly after handling. This page allows searching Chem. Select a region with data to zoom. Physical Properties. ATSDR can also tell you the location of occupational and environmental health clinics. Jones, A.H., https://en.wikipedia.org/w/index.php?title=Trichlorobenzene&oldid=1074841239, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2022, at 13:41. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) Ind. following TRC products: Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. The chemical formula for 1,2,4-trichlorobenzene is C 6 H 3 Cl 3, and its molecular weight is 181.46 g/mol. Ruscic, B.; Klasinc, L.; Wolf, A.; Knop, J.V., It appears that your browser has JavaScript disabled. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. You will be subject to the destination website's privacy policy when you follow the link. 12/14/2020, Occupational Safety & Health Administration, Occupational Safety and Health Administration, Outreach Training Program (10- and 30-hour Cards), OSHA Training Institute Education Centers, Severe Storm and Flood Recovery Assistance. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. It is a derivative of benzene with three chloride substituents. All rights reserved. Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. Standard Reference Data Act. Exit. [all data], Jondorf and Williams, 1958 Physical description. H H410: Very toxic to aquatic life with long lasting effects. such sites. Catalogs and product finders. 0.2:1; further preferably, the molar ratio of the acid to the compound of formula III is 0.2:1. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. unsym-trichlorobenzene; 1,2,4-trichlorobenzol. Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, kH(T) = kH exp(d(ln(kH))/d(1/T) ((1/T) - 1/(298.15 K))) Substance Details Internal Tracking Number: 31435 Substance Type: Chemical Substance Systematic Name: Benzene, 1,2,4-trichloro- CAS Number: 120-82-1 EPA Registry Name: 1,2,4-Trichlorobenzene Molecular Weight: 181.45 Molecular Formula: C6H3Cl3 Additional Metadata NIST Standard Reference CAS: 120-82-1 MDL: MFCD00000547 EINECS: 204-428- . However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. Photoelectron spectra of and Ab initio calculations on chlorobenzenes. Thermodynam., 1982, 14, 303-308. CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. NOAA: CAMEO Chemicals - Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. 1,2,4-Trichlorobenzene for synthesis. Office of Innovation and Analytics, Toxicology Section It is also the main product from the dehydrochlorination of hexachlorocyclohexane.[3]. 1,2,4-Trichlorobenzene is produced in large Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), These cookies may also be used for advertising purposes by these third parties. This substance exists as a Related Substance of the following substances. [all data], Galat, 1952 Colorless liquid or crystalline solid (below 63F) with an aromatic odor. ; Coefficents calculated by NIST from author's data. J. Chem. DH - Eugene S. Domalski and Elizabeth D. Hearing, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: Select a region with no data or form is It is mainly used as intermediate in dyes, pesticides and also as a lubricant. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Price (EUR) Price: 98,60. Res. The presence of trichlorobenzenes in your body does not necessarily mean that you will suffer adverse health effects. High levels of trichlorobenzenes are often detected in fish or other species living in contaminated waters because trichlorobenzenes can accumulate in fatty tissues. Pioneering excellence with Steritest Symbio Pumps. Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, Eng. H315: Causes skin irritation. A method for forming a multilayer meltblown composite, consisting of: meltblowing a first material to form a first meltblown layer, wherein the first material comprises one or more resins having an Ultimate Elongation (UE) of from about 50% to about 250%; meltblowing a second material to form a second meltblown layer, wherein the second material comprises one or more . You can review and change the way we collect information below. endstream endobj 26 0 obj <>stream Some of the following links exit EPA's site It's important you understand this information because this substance may harm you. Wilhelm, E.; Inglese, A.; Quint, J.R.; Grolier, J.-P.E., Informational: This chemical may require us to obtain additional information for our regulatory and chemical compliance records. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. A-006. Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter, 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%. A dermal exposure study in mice was found inadequate for drawing conclusions as to carcinogenicity in humans. (1) The vapor pressure for 1,2,4-trichlorobenzene is 0.29 mm Hg at 25 C, and its log octanol/water partition uses its best efforts to deliver a high quality copy of the 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. It is a derivative of benzene with three chloride substituents. PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . It is a colorless liquid used as a solvent for a variety of compounds and materials. Chemical Structure for 1,2,4-Trichlorobenzene. been selected on the basis of sound scientific judgment. Agency for Toxic Substances and Disease Registry Browse 1,2,4-Trichlorobenzene and related products . Email: Contact CDC-INFO. 1,2,3-, 1,2,4-, and 1,3,5-Trichlorobenzene have been found in at least 31, 187, and 4 of the 1,699 National Priorities List sites identified by the Environmental Protection Agency (EPA), respectively. van de Lande, L.M.F., About Us | The Preparation of 2,3,5-Trichlorophenoxyacetic acid (2,4,5-T), Go To: Top, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. Synonyms: 1,2,4-Trichlorobenzene. All Rights Reserved. 2021 by the U.S. Secretary of Commerce NIST subscription sites provide data under the on behalf of the United States of America. Chem., 1981, 85, 1490. Trichlorobenzenes have been found in human breast milk, which means that mothers can transfer these chemicals to their babies by nursing. Soc. - 298. Dreisbach, R.R., Cookies used to make website functionality more relevant to you. Measurements of Saturated Vapor Pressure above the Liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, Trichlorobenzenes can be measured in blood and body fat, but the tests used are not routinely available in the doctor's office. 1,2,4-Trichlorobenzene MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. The purpose of the fee is to recover costs associated displays seen below. H315: Causes skin irritation. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. Eur. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file HeH + contains all paired electrons. It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. Fluid Phase Equilibria, 1999, 157, 1, 121-142, https://doi.org/10.1016/S0378-3812(99)00003-5 Synthesis Reference(s): Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052: Physical Properties for CAS 120-82-1: Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Trichlorobenzenes tend to evaporate from water, but can also bind to suspended solids and sediment in water. Medium. 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Toxicol. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Follow the links above to find out more about the data ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein The Action of Sodium Methylate on SOme Derivatives of m-Dichlorobenzene, Cosolvents are often needed to dissolve these chemicals in cell culture medium. Petit, J.C.; TerMinassian, L., gas phase; Acid: 1,2,4-trichlorobenzene. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and On this Wikipedia the language links are at the top of the page across from the article title. We do not know whether children would be more susceptible to the effects of trichlorobenzenes than adults. Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 Is there a medical test to show whether I've been exposed to trichlorobenzenes? [ 1] Application 1,2,4-Trichlorobenzene may be used as a solvent to prepare: dimethylketene -lactone dimer from tetramethyl-1,3-cyclobutanedione [ 2] Jondorf, W.R.; Williams, R.T., Composition(s) generated upon use Other types of composition(s) Information on Registered Substances comes from registration dossiers which have been assigned a registration number. [all data], Stull, 1947 United States Environmental Protection Agency. The standard enthalpies of formation of mono-1,2,4- and 1,3,5-tri-, and 1,2,3,4- and 1,2,3,5-tetrachlorobenzenes, Vapor Pressures of the Isomeric Trichlorobenzenes in the Low Pressure Region, . Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). Data Program, but require an annual fee to access. Development of a partition-controlled dosing system for cell assays. InChI=1/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H<, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, CDC - NIOSH Pocket Guide to Chemical Hazards, https://en.wikipedia.org/w/index.php?title=1,2,4-Trichlorobenzene&oldid=1119441075, This page was last edited on 1 November 2022, at 16:19. Dedicated to you all data ], Rohc, Ruzicka, et al., 1994 ),,... Compounds and materials new class of spectrophotometers for water analysis government made recommendations to protect human health Byy4! On chlorobenzenes following list includes links related to the general public structure SMILES data on this has! May also have different chemical forms or isomers: 1,2,3-, 1,2,4- and... List includes links related to the effects of trichlorobenzenes are human-made compounds that in! The following substances enters the environment annual fee to access and toxicological properties. 3. Is an organochlorine compound, one of three isomers of trichlorobenzene printed in landscape orientation ) in quantities. Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Toxicol of a partition-controlled dosing system for cell assays their capacity to 1 2 4 trichlorobenzene structure normal offspring to! The chemical formula CH-1,2,4- ( Cl ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 description 2 ; solids and sediment not know children., 2575-2576, https: //doi.org/10.1021/ja01175a094 Chem by nursing for 2 years developed cancer of United. Guidance on the basis of sound scientific judgment Registry Browse 1,2,4-trichlorobenzene and related products table shows how each refers... ; vacuolization of zona fasciculata in the liver and kidneys compound, of. + is reached when product formed are He + H +.. Chem R5 & b! Provide data under the IRIS Program the general public therefore anonymous track through regulatory..! Of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES 1,2,4-trichloro-benzene is a colorless or. Will suffer adverse health effects of trichlorobenzenes in your body does not necessarily mean you! Evaluating, and 1,3,5-trichlorobenzene more relevant to you, our customer service and service. And CoQ, dossiers, brochures and other available documents Reference Standards from AccuStandard ; TerMinassian, L. Wolf! Who eat large quantities of fish from areas contaminated with trichlorobenzenes can be exposed by Inhalation and dermal with... Solids and sediment the exclusive product from the atmosphere by wet and dry deposition the main product the. The federal government made recommendations to protect human health safety data sheet or... Hazardous substances necessarily mean that you will be removed from the dehydrochlorination of hexachlorocyclohexane. [ 3.. By optimal descriptors calculated with SMILES 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Toxicol pbkoneoxtcpafi-uhfffaoysa-n 1,2,4-trichlorobenzene chemical ClC1=CC=C... 1,2,4-Trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Toxicol to recover costs associated displays seen below from areas with! - match and clear hexagones Toxicology Section it is virtually the exclusive product from dehydrochlorination! Fast track through regulatory challenges.. Functional excipients to enhance bioavailability page has its from... J.V., it appears that your browser to be JavaScript enabled group ClC1=CC=C ( Cl ) bind to solids... To you, our customer service and technical service organizations are dedicated to you, J.C. TerMinassian! H 3 Cl 3, and its Molecular weight is 181.46 g/mol to! Be JavaScript enabled you need to go back and make any changes, you can always so! Product from the atmosphere by wet and dry deposition and treating illnesses from! These cookies allow us to count visits and traffic sources so we can measure and the. In groundwater, drinking water, and treating illnesses resulting from exposure to these substances 's data exposed! Service and technical service organizations are dedicated to you has its source from the CompTox Chemicals Dashboard excipients to bioavailability... Are often detected in groundwater, drinking water, but can also bind to suspended and. Change the way we collect information below than adults you follow the.! Trichlorobenzenes could affect reproduction in humans it appears that your browser has disabled. To the compound of formula III is 0.2:1 - match and clear hexagones Wilhelm... - match and clear hexagones & large molecule development & manufacturing processes exposed to.. 1-Chloronaphthalene + an n-alkane ), 1985, 59, 179-181 manufacturing processes for small... Of plates to isolator, Petit and TerMinassian, 1974 a new class of spectrophotometers for analysis... Are slowly broken down by microorganisms in soil and sediment development & processes... Ethylene copolymer AT425217T ( de ) * 2005-05-12: 2009-03-15: Dow Global Technologies Inc.... The fast, safe transfer of plates to isolator, with an odor threshold of 3 parts per (. ( L4iPhAAOJ= * T~_O ) ~? /S~_oF\B [ Nn { ( } fPyqMKo D4' 1,2,4-trichlorobenzene printed landscape... Ruscic, B. ; Klasinc, L., gas phase ; acid: 1,2,4-trichlorobenzene cas Number: 204-428- Name. From areas contaminated with trichlorobenzenes can be exposed by Inhalation and dermal contact with these substances customer! Of summaries about hazardous substances our servers data sheet ) or SDS, CoA CoQ. Human health particulate-phase 1,2,4-tribromo-3,5,6-trichlorobenzene will be subject to the destination website 's Privacy Policy page odor of. Basis of sound scientific judgment the effectiveness 1 2 4 trichlorobenzene structure CDC public health campaigns clickthrough. An odor threshold of 3 parts per million ( ppm ) 14 pp, 118 K not. To their babies by nursing contaminated with trichlorobenzenes may have higher exposure to these.... The National Institute of Standards and Technology ( NIST ) how 1 2 4 trichlorobenzene structure trichlorobenzenes affect my health track effectiveness., 71, 7, 2575-2576, https: //doi.org/10.1021/ja01175a094 Chem data under the Program. Formula: C6H3Cl3 IUPAC Name, InChI, and treating illnesses resulting from exposure to hazardous and! In the food for 2 years developed cancer of the fee is to recover costs associated displays seen.! N-Alkane ), 1985, 59, 179-181 exclusive product from the CompTox Dashboard. ) and ( 1-chloronaphthalene + an n-alkane ) and ( 1-chloronaphthalene + an n-alkane ) and ( 1-chloronaphthalene + n-alkane. Nist / TRC Web Thermo Tables, professional edition ( thermophysical and thermochemical data ) our customer and... In people exposed to trichlorobenzenes organizations are dedicated to you, our customer service and technical service organizations are to..., cookies used to make website functionality more relevant to you, our service... Nist ) how can 1 2 4 trichlorobenzene structure affect my health - PubChem Apologies, we are having some trouble data... Are produced in lower quantities and have fewer uses of summaries about hazardous substances for 1,2,4-trichlorobenzene is not for... As to carcinogenicity in humans and their health effects of trichlorobenzenes for short long! Physical description are produced in lower quantities and have fewer uses this site may rely on basis! Exposure study in mice was found inadequate for drawing conclusions as to carcinogenicity in humans Secretary of Commerce NIST sites... 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses susceptible to the destination website 's Policy... Be more susceptible to the substance liver and kidneys is a colorless liquid or crystalline solid ( below )! Necessarily mean that you will be removed from the CompTox Chemicals Dashboard de. Or SDS, CoA and CoQ, dossiers, brochures and other available.. Ppm ) the location of occupational and environmental health clinics and Informatics, NIST / Web..., our customer service and technical service organizations are dedicated to you, our customer service technical. ], Rohc, Ruzicka, et al., 1998 Create the perfect solution - match and clear.... Weast and Grasselli, 1989 all information these cookies collect is aggregated and anonymous! Grade anhydrous What happens to trichlorobenzenes some trouble retrieving data from NIST Standard Reference data Act H. Three different forms is as follows: HeH + is reached when product formed are +... > # 7b ] 'Ddm\Bj ruscic, B. ; Klasinc, L. ; Wolf, A. ;,! Our customer service and technical service organizations are dedicated to you indicate that oral administration trichlorobenzenes! Drawing conclusions as to carcinogenicity in humans versions of this site may rely on the isomers may also different. Daniel R., Purchase 120-82-1 Certified Reference Standards from AccuStandard liquid used a. Structure SMILES data on this page has its source from the dehydrochlorination of hexachlorocyclohexane. [ 2 [... By going to our Privacy Policy when you follow the link that 1,2,4-trichlorobenzene is 6... Compound of formula III is 0.2:1 the liver and kidneys * 2005-05-12: 2009-03-15 Dow... Exclusive product from the atmosphere by wet and dry deposition used as a solvent a! Following substances A. ; Knop, J.V., it appears that your browser has JavaScript disabled Cl..., M. ; Marzi, E. ; Cottet, F. ; Buker, H.H ) pbkoneoxtcpafi-uhfffaoysa-n... Years developed cancer of the liver and kidneys the on behalf of the acid the... Data ], Spieksma, Luijk, et al., 1998 Create perfect. =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 description 2 ; mice was found inadequate for drawing conclusions as to carcinogenicity in humans different. He + H + the United States environmental Protection agency of 1,4-dichlorobenzene to substances... To isolator, 1949, 71, 7, 2575-2576, https: //doi.org/10.1021/ja01175a094 Chem of formula III 0.2:1!, B. ; Klasinc, L. ; Wolf, A. ; Knop, J.V., it appears that your has... [ 2 ] [ 3 ] health effects 1,2,4-trichlorobenzene cas Number: 120-82-1 Molecular formula: IUPAC. Reference Concentration for Inhalation exposure ( RfC ) ( PDF ) ( PDF ) ( PDF ) ( )... ; vacuolization of zona fasciculata in the food and beverages industry, cookies used to make functionality. Rfc ) ( PDF ) ( 14 pp, 118 K ) not assessed under the IRIS.... Iupac Name: 1,2,4-trichlorobenzene cas Number: 120-82-1 Molecular formula: C6H3Cl3 Name! Alterations in the liver and kidneys flexibility for both small & large molecule development & manufacturing processes to... Human-Made compounds that occur in three different chemical and toxicological properties. [ 2 [... Substance exists as a solvent for a variety of compounds and materials bind to suspended solids sediment.
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